In this population-based study of reported cases of amniotic fluid embolism, the maternal mortality rate (26.4%) was significantly less than previously reported and might reflect a more accurate population frequency. The cesarean rate was 60% and the frequency of fetal distress was 49%. The average maternal length of stay for survivors was 6.5 days (range 3-27 days, median 5 days). Among the 14 women who died, the frequency of DIC (79%) and hemorrhage (71%) was not different compared with that of the survivors (62% and 72%, respectively), but obstetric shock was higher (86%, P =. There were 35 (66%) diagnoses of disseminated intravascular coagulation (DIC), 38 (72%) diagnoses of hemorrhage, and 25 (47%) diagnoses of obstetric shock. Fourteen women with amniotic fluid embolism died, for a maternal mortality rate of 26.4%. Fifty-three singleton gestations had the diagnosis of amniotic fluid embolism, for a population frequency of one per 20,646 deliveries. There were 1,094,248 deliveries during that 2-year period. All cases of amniotic fluid embolism were examined for other pregnancy complications. This database covered all singleton deliveries that occurred in 328 civilian acute-care hospitals in California, which represented 98% of all deliveries in California. To examine the risk factors and pregnancy outcomes associated with 53 cases of amniotic fluid embolism that occurred in California during the 2-year period Januto December 31, 1995.ĭata were obtained from a computerized database that contains linked records from the vital statistics birth certificate and hospital discharge summaries of both mother and newborn.
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